Pirarubicin synthesis
WebbPirarubicin is a new kind of anthracene nucleus broad-spectrum antitumor antibiotic. This compound was rapidly incorporated into tumor cells, inhibiting DNA polymerase alpha, … Webb16 apr. 2024 · Pirarubicin, an anthracycline antibiotics, is a topoisomerase II Inhibitor. Pirarubicin has widely application in intravesical chemotherapy for bladder cancer, but …
Pirarubicin synthesis
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WebbSynthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin. by Kenji Tsukigawa, Long Liao, Hideaki Nakamura, Jun Fang, Khaled Greish, Masaki Otagiri, Hiroshi Maeda. Cancer science. Read more related scholarly scientific articles and … Webb30 dec. 2024 · In a previous study, we reported on the development of a synthetic polymer conjugate of pirarubicin (THP) that was formed via an acid-labile hydrazone bond …
WebbThe invention discloses a steady freeze drying medicament which mainly contains pirarubicin, oiliness carrier, surface activator, cryodesiccation sustaining agent, and intralipid with an even grain diameter less than 1000nm is freezed and dried. The redissolved grain size is less than 2000nm, and the pH lever of the fluid is between 4 and … Webb25 nov. 2004 · The copolymer of styrene-maleic acid (SMA) was used to construct micelles containing pirarubicin (4‘-O-tetrahydropyranyladriamycin, or THP) as a new anticancer …
WebbPreviously, we prepared a pirarubicin (THP)-encapsulated micellar drug using styrene-maleic acid copolymer (SMA) as the drug carrier, in which active THP was non … Webbピラルビシン（Pirarubicin、THP）はアントラサイクリン系の薬剤の一つであり、抗悪性腫瘍性抗生物質であるドキソルビシンのアナログである。 ピラルビシンはDNAの隙間にインターカレートしてトポイソメラーゼIIを阻害し、結果としてDNAの複製や修復、RNAやタンパク質の合成を阻害する。
WebbThe invention discloses a kind of preparation and use of the polymer of grafting drug, can specially be grafted the star polymer containing anthracycline antibiotic structure and preparation method and purposes.The anthracycline antibiotic Grafting Star-shape polymer is more better in the treatment of age-related macular degeneration disease than the …
Webb21 dec. 2024 · Visit ChemicalBook To find more Pirarubicin(72496-41-4) information like chemical properties,Structure,melting point,boiling point,density,molecular … hayes typology of organisation changeWebbCN104203252A CN201380018749.2A CN201380018749A CN104203252A CN 104203252 A CN104203252 A CN 104203252A CN 201380018749 A CN201380018749 A CN 201380018749A CN 104203252 A CN104203252 A CN 104203252A Authority CN China Prior art keywords pirarubicin hydrochlorate maltose injection weight ratio Prior art date … botox tussWebbPirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication. … hayes \u0026 finch candlesWebb22 dec. 2014 · Pirarubicin (4′-O-tetrahydropyranyldoxorubicin, THP), a semisynthetic derivative of doxorubicin, 1 is one of the anthracycline antitumor drugs used clinically for … hayes \u0026 finchWebb30 mars 2024 · Competitions Essay Year Economics 12. Many Americans may think the Year 12 Economics Essay Competitions constitution is just a piece Literarischen Essays On Abortion of old paper. Look up citizenship in Wiktionary, Essay For Networking the free dictionary. Technology Definition Essay On Beauty hayes \u0026 finch candle oilWebbPirarubicin (NSC-333054) is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II , used as an … hayes \u0026 co printing incWebb2007-12-05. Pirarubicin Hydrochloride is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic … hayes \u0026 finch altar breads