WebApr 8, 2024 · As a person with diabetes gets older, simplification, switching or de-escalation of the therapeutic regimen may be necessary, depending on their level of frailty and HbA1c levels. Consideration should be given, in particular, to de-escalation of therapies that may induce hypoglycaemia, such as sulphonylureas and shorter-acting insulins. WebA target HbA1c should be set between 6.5% (48 mmol/mol) and 7.5% (59 mmol/mol), based on the risk of macrovascular and microvascular complications. In general, the …
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WebIn the absence of reliable data on elderly and frail diabetic patients, some specialists recommend raising the HbA1c target to 8.5% or 9%. Elderly diabetic patients: target an HbA1c of about 8.5% Prescrire Int. 2013 Nov;22(143):272. PMID: 24427844 Abstract In the absence of reliable data on elderly and frail diabetic patients, some specialists ... WebGlycaemic targets for some elderly people may be higher than for the non-elderly (eg a glycated haemoglobin [HbA1c] target of 8% [64 mmol/mol], rather than 7% [53 … frameworks for product management
Diabetes and Aging: From Treatment Goals to Pharmacologic Therapy
WebMar 30, 2024 · Dulaglutide showed a reduction in HbA1c as early as 4 weeks after initiation of treatment, which was maintained over 26 weeks in both age groups. The percentage of patients achieving HbA1c target < 7.0% at 26 weeks was also similar in both age groups. Incidence of hypoglycemia and GI TEAEs was low in each age group. WebOvertreatment of diabetes is common in older adults and should be avoided Reference Grade: B De-intensification (or simplification) of complex regimens is recommended to reduce the risk of hypoglycaemia in older … WebThe proportion achieving their individual HbA1c target was lower for <65-year-olds (46.0% vs 54.3% and 54.7%; p<0.02). Symptomatic hypoglycemia incidence was more common in the ≥75-year-old group (3.4% vs 1.4% and 1.4%; p=0.0126). Conclusions BOT with Gla-100 results in similar improvements of glycemic values with low risk of hypoglycemia ... frameworks for mobile app development