2024 Atf4 kda

Atf4 kda

Author: oitn

August undefined, 2024

WebCara M. Anderson, Kay F. Macleod, in International Review of Cell and Molecular Biology, 2024 2.1.1 ATF4 induces autophagy during the integrated stress response. ATF4 is a basic leucine zipper (bZIP) stress-responsive transcription factor that belongs to the CREB/ATF family of transcription factors that are able to homodimerize or heterodimerize to regulate … WebDuring the UPR, PERK can phosphorylate eIF2α, the 90-kDa precursor of ATF6 is cleaved into a 50-kDa protein that functions as a transcription factor, and IRE1 splices a 26-bp intron from Xbp1u, resulting in an active Xbp1s. ... ATF4-F: ATGACCGAAATGAGCTTCCTG: ATF4-R: GCTGGAGAACCCATGAGGT: GADD34-F: GGAGGAAGAGAATCAAGCCA: …

ATF4 Antibody 60035-1-Ig Proteintech

WebFeb 28, 2006 · AMSOIL Synthetic Universal ATF / ATF+, ATF+2, ATF+3, ATF+4 _____ Maybe this helps ..... ONLY ATF+4 (or you can consider AMS OIL Synthetic Universal … WebBackground: ATF4. ATF4 is an approximately 38 kDa member of the bzip family of transcription factors. It plays an important role autophagy, the unfolded protein response, … spinners just can\u0027t get you off my mind

ATF4 Gene - GeneCards ATF4 Protein ATF4 Antibody

WebMay 15, 2015 · ATF4 is a transcription factor whose mRNA translation is stimulated in response to stress-activated eIF2alpha kinases. Established conditions that activate eIF2alpha phosphorylation and ATF4 translation include excessive stress in the endoplasmic reticulum (ER) and amino acid deprivation. ... The resulting ~50 kDa His … Web1X10^6 HeLa cells were intracellularly stained with 0.4 ug Anti-Human ATF4 (60035-1-Ig, Clone:3E4C5) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG (H+L) at dilution 1:1000 (red), or 0.4 ug Control Antibody. Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011). WebATF4 also regulates glucose homeostasis by suppressing beta-cell proliferation and insulin production. Furthermore, ATF4 targets the histone demethylase JMJD3 to alter chromatin structure and enhance gene transcription in response to amino acid deprivation. ... ~48 kDa observed. The calculated molecular weight is 39 kDa; however, this protein ... spinners inc cedar rapids ia

ATF4 antibody (28657-1-AP) Proteintech - ptglab

CHOP (L63F7) Mouse mAb Cell Signaling Technology

WebProduced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal [EPR24346-182] to ATF-4 WebChIP. Chromatin immunoprecipitations were performed with cross-linked chromatin from MEF wild-type cells treated with tunicamycin (2ug/ml) overnight, and CHOP (L63F7) Mouse mAb #2895 or Normal Rabbit IgG #2729 using SimpleChIP ® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. The enriched DNA was quantified by real-time PCR using … spinners jamaicanWebThe transcription factor ATF4 enhances bone formation by favoring amino acid import and collagen synthesis in osteoblasts, a function requiring its phosphorylation by RSK2, the kinase inactivated in Coffin-Lowry Syndrome. ... Ribosomal Protein S6 Kinases, 90-kDa / metabolism Substances Amino Acids Atf4 protein, mouse Dietary Proteins ... spinners jupiters casino

"WebSep 28, 2024 · ER-resident 75 kDa glucose-regulated protein (GRP75) and mitochondrial voltage-dependent anion channel 1 (VDAC1) form a complex with subtype 3 of the 1, 4, 5-triphosphate receptor (IP3R3). ... Furthermore, strong binding of ATF4 to a 5′ upstream region of Sig1r was observed by a chromatin immunoprecipitation assay, suggesting that … " - Atf4 kda

Atf4 kda

ATF-6 (D4Z8V) Rabbit mAb Cell Signaling Technology

WebMar 28, 2024 · Methods. Hepatocyte-specific ATF4 deficient MUP-uPA mice (MUP-uPA/Atf4 Δhep) and control MUP-uPA/Atf4 F/F mice were fed high fat diet (HFD) to induce NASH-induced HCC, and Atf4 F/F and Atf4 Δhep mice were injected with diethylnitrosamine (DEN) to model carcinogen-induced HCC. Histological, biochemical, … WebWestern blot: Approx 35-37 kDa band observed in Mouse Heart lysates (calculated MW of 38.3 kDa according to Mouse NP_001274109.1; NP_033846.2). ... ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded ...

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WebMay 12, 2024 · ABSTRACT. Purpose: To determine concentrations of endoplasmic reticulum (ER) stress-related factors activating transcription factor 4 (ATF4) and glucose-regulated 78 kDa protein (GRP78) in vitreous and aqueous humor (AqH) of patients with proliferative diabetic retinopathy (PDR) and the correlation of ATF4, GRP78 and inflammatory … WebAnti-ATF4 Antibody Anti-ATF4 is an antibody targeting the ATF4 protein, validated for use in WB & ChIP. - Find MSDS or SDS, a COA, data sheets and more information. United States / English; Quick Purchase; My Favorites ... The calculated molecular weight is 39 kDa; however, this protein may be observed at ~48 kDa in human tissue lysates and ~45 ...

WebRecent studies have revealed that the central nervous system, particularly the hypothalamus, is critical for regulating insulin sensitivity in peripheral tissues. The aim of our current study is to investigate the possible involvement of hypothalamic activating transcription factor 4 (ATF4) in the r … WebCadmium exposure causes endoplasmic reticulum (ER) stress and accumulation of activating transcription factor 4 (ATF4), an ER stress marker. To elucidate the role of …

WebHowever, CS-11815 detects a band with a mass of ~49 kDa, while the expected molecular weight of ATF4 is ~38 kDa. In contrast, SC-200 is a very dirty polyclonal antibody, but it seems to detect ATF4 as both a ~49 kDa band and a ~38 kDa band. I'm unaware of any long ATF4 splice variants or PTMs that might be responsible for this difference.

WebThis antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen. The antibody recognizes the 38 kDa ATF4 protein and its phosphorylated forms (50 …

WebATF4 can bind DNA as a homodimer and as a heterodimer. ATF4 is ubiquitinated by SCF(BTRC) in response to mTORC1 signal, followed by proteasomal degradation and leading to down-regulate expression of SIRT4, so the molecular weight of … spinners just to be with you lyricsWebJan 18, 2024 · Endoplasmic reticulum (ER) stress and inflammation are hallmarks of myocardial impairment. Here, we investigated the role of the stress response protein regulated in development and DNA damage 1 (REDD1) as a molecular link between ER stress and inflammation in cardiomyocytes. In mice fed a high-fat high-sucrose (HFHS, … spinners loft hawksheadWebMay 31, 2010 · This suggests that the HIF and BCL2/adenovirus E1B 19-kDa protein-interacting protein 3 pathway may be less important under chronic and severe hypoxia … spinners just as long as we have loveWebMar 22, 2024 · Moreover, the secretion of CCL2 in cancer milieu is regulated by activating transcription factor 4 (ATF4), ... (IFN) γ-induced protein; IP-10) is a 10 kDa protein functionally classified as a Th1 chemokine. It binds to the CXCR3 receptor and regulates the immune response by activating inflammatory cells such as T lymphocytes, eosinophils, … spinners just to be with youWebAll lanes : Anti-ATF6 antibody (ab83504) at 1 µg/ml Lane 1 : Wild-type HeLa cell lysate Lane 2 : ATF6 knockout HeLa cell lysate Lysates/proteins at 20 µg per lane. Performed under … spinners leaving of liverpoolWebDec 28, 2024 · The Golgi apparatus is involved in the intracellular transport and maturation of proteins and lipids (Rohn et al., 2000; Viotti, 2016).More than a third of all human genes are known to encode proteins that travel through the Golgi (Yuen et al., 1997).The Golgi has a distinctive structure with several layers of flat, semicircular vesicles known as cisternae. spinners live youtubeWebSep 29, 2024 · ATF-4 Antibody (B-3) is an IgG 2b κ mouse monoclonal ATF-4 antibody (also designated ATF4 antibody, cAMP-dependent transcription factor ATF-4 antibody, … spinners living a little laughing a little